After initial contact they did. Beavers were almost wiped out to trade for it and whisky.
Colonists had numbers, the latest tech, and murderous greed and deceit on their side.
Musket vs cannon hardly evens the playing field.
And when the Native Americans did have the advantage, other more effective tactics were deployed, like legally binding peace treaties which were enforced only to the advantage of the US Gov't and otherwise disregarded, and other wonderful things such as handing out free yellow fever contaminated blankets, and killing off millions of bison down to a mere 500. Broken promises, disease and starvation - as also deployed by tyrants elsewhere - are far cheaper and more effective in the long term than guns and soldiers.
You can't eat a gun while freezing to death when supplies are cut off.
Heck, nowadays, turn off the power grid for less than a week in August, and millions of Southerners die without that percious AC.