I pressed ctrl+shift+show windows key (aka the one with the square with 2 lines next to it) and took a screenshot of the top image, and if you go to the bottom right in a new tab, you can upload your own image and change the backround.
You are literally looking at a painting that was created (with other paintings) from 1508 to 1512 that got photo shopped with a bunch of memes. I’m 100% sure the painting of god pointing which was made from 1508 to 1512 was created before the cartoon: spider man.
I'm talking about the pointing in context. ;)
In this gathering of pointers, Spider-Man may very well have been the first to engage in the point off that we see here.