As a man who has a higher-than-average female and LGBTQ+ friend base, I have yet to run into a single person who was "friendzoned" who isn't a straight male. Like, ever. So while, yes, I'm absolutely making an assumption that may be inaccurate in this instance, my personal experience informs that assumption.
As for my assumption that the meme was based on its (no apostrophe! Sorry, I'm that guy) creator, yeah, my bad there. I was wrong.