I didn't figure it was. I'm a girl.
The original meme was kinda about how some women feel the need to be mean to (not just politely decline) men who show interest (not the skeevy pickup lines).
If a guy asks if he can have a girls number, it's perfectly okay to say "no, I'm not interested." I just don't thinks it's necessary to call him a loser, jerk, ect. But many women do.