The fact that they live with the threat of violence in some of those red areas. A trans coworker of mine actually has to go in drag as their sex assigned at birth to be safe while traveling in some parts of the country.

Or they could just accept their given gender at birth & deal with whatever mental situations make them think they are actually the opposite sex.

I know one guy - who started dressing up lady like. Because he was effeminate & thought he was actually a girl. In conversation - he told me why he was doing things like that, it was mostly because of an abusive parenting situation. Both parents weren't very accepting that he was girly. I let him know there's nothing wrong with being a girly dude & made him aware of the many ways I'm girly myself. That really opened his eyes.

Turns out - he was just a girly dude. He went back to being a girly dude & found himself a woman who was more take charge & guy like in behavior. They make a wonderful couple and neither of them has to dress up like the other gender to do it.

Well, yes, there's a gender spectrum: it's fine to be a girly dude, or a buff lady, or whatever, but there is a smaller segment of people who are (in simplified terms) born with a brain that's gendered differently than their body.

For those people, becoming and fully expressing who they are is essential, even life-saving. It doesn't hurt anyone else: it's just about them. No petty personal or cultural biases of ours should stop them.

The transperson I'm closest to comes from a very healthy, loving family, has a wonderful marriage, is a sensible, reliable caring leader at her job. It's time to stop calling transpeople less-than or mentally ill and just accept them as humans who are different than us.