Sorry you're having trouble. When you say "use it a second time", what exactly is the order of operations? Are you generating a meme then clicking "new" and getting the "reset to empty template" pop-up?
One thing you could try is resetting your browser's cache/cookies, could solve the problem.
Happens on mobile sometimes. When the meme generator is used more than once, dragging and resizing in text boxes and the draw button might become unresponsive. Templates and the text in text boxes work fine.
I just realized that when I use the meme generator and use it a second time, I can't move text boxes or added images, and can't use the draw tool without closing the tab and opening it again, would appreciate help on this.