I'm speaking on the middle eastern conflict. As far as poverty goes you can only work towards ending it for yourself because it's an endemic to humanity to be greedy and/ or make bad choices, you can't magically make everyone comfortable you can only try to ease their suffering. Upward mobility is hard work and there are limited options and outcomes. For cancer, that's natures form of population control, sickness is our only natural predator, cure one thing, a new thing pops up. We nearly eradicated polio but now COVID is a thing as one example. Brutality is a part of human nature and everyone is capable of it and falls prey to weak moments of cruelty and mistreatment. The world is not sunshine and rainbows, some problems can never be solved.