The first case was reported in 1977 of a patient wanted to amputate their own limbs, because the patients felt it didn't fit their body. The initial assessment was attributed to a sexual nature, because all of the first cases were sexually motivated. But years later, other cases arose that weren't not "entirely" sexual in motivation. The first actual surgical amputation for this dysphoria wasn't until 1997. In 2020, researchers discovered that in all of the dysphoria patients, their right parietal lobe had less dense gray matter and less neural activity than the control group. This portion of the brain is responsible for sensorimotor awareness, such as "feeling" your leg is still there ever after it's amputated. Gender dysphoria was always diagnosed as an acute form of "body integrity dysphoria" until just a few years ago.
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