One of the theories of the end of the universe is heat death where everything reaches a constant temperature. Therefore in the distant future it will be impossible for there to be any change at all. If the theory is correct.
No man ever steps in the same river twice, for it's not the same river and he's not the same man. There is nothing permanent except change. -- Heraclitus; I took a look at my life and saw that it too was a river, and the boy Siddhartha was separated from the man Siddhartha and from the graybeard Siddhartha only by shadows, not by anything real. -- Hesse