The picture to me hold more emotion than any other meme template I've looked at.
The closed off nature of picture (the window and a girl), showing a girl alone or isolated. She is also looking at herself as well, which to me conveys sadness. It may be that she has a low view of herself, the reflection of lonliness, or the fact that she could no longer go outside (reflecting today's coronavirus trouble), The rain adds to the latter notion as she might get sick as a result.