No, she wan't. There were nine government agencies who had to sign off on that deal. Hillary was not personally involved because that was not something the secretary of State did.
At the time, the New York Times received a statement from former assistant secretary Jose Fernandez, who was appointed to the CFIUS during the Uranium One deal. “Mrs. Clinton never intervened with me on any C.F.I.U.S. matter,” Fernandez told the Times.
So while Clinton may have been briefed on the matter, according to Fernandez, the secretary did not personally approve the deal.
The Uranium One controversy involves various conspiracy theories promoted by conservative media, politicians, and commentators that characterized the sale of the uranium mining company Uranium One to the Russian state-owned corporation Rosatom as a $145 million bribery scandal involving Hillary Clinton and the Clinton Foundation. No evidence of wrongdoing was ever found.