GIF from Netflix/Nickelodeon Cartoon series "Glitch Techs" (2020), from the episode "Castle Crawl", the stressed out girl in that GIF is called Miko, I have to clarify all of those things mentioned before just in case you don't know where does the GIF come from. In my opinion, her expressive character in that show is quite good for memes.

Image from "Glitch Techs" (2020), Episode is "Age of Hinobi", the purple-haired character in that stupid meme I made is called Miko in case you don't know. there's no tag for glitch techs, which makes sense since it's not as popular as all other perfectly-crafted animated shows of the time, but it's still worth watching anyway, it's still there on Netflix, you can watch it there if you want.