Tanjiro loses, Thanos themself can make a shield that can withstand a planet-destroying attack, survived three planet-destroying attacks, survived a black hole, is strong enough to lift 50 quintillion tons, is fast enough to match silver surfer's speed, and is resistant to a gun specifically made to kill him. 1) MCU nerfed a lot of the characters in the comics and this is mostly based on comics, 2) MCU probably would still defeat them
