Great point. As I've often heard, autism is the sun and the kryptonite. I do like having someone else on here that has the X-Men hypothesis for autism where it's just the next step of humans evolving in response to their environment, only this time it's an environment we created ourselves. A digital landscape that we're more adapted to naturally. I think it will eventually become the norm the more we advance.
So each individual section of the brain in an autistic person has more neural connections within those sections than a neurotypical brain. However the neural connections that exist between the different sections of the brain that connect them to each other are fewer. Knowing that makes me think that if something like "small talk" requires multiple different processes or "areas of the brain" being used at once that it would make sense that it would be more difficult for neurodivergent brains. I think this also explains a lot of the more savant/prodigy trends with neurodivergence as well.
I recently read that the "wiring" that is different in autistic brains is that we have more connections in each individual section of the brain, but less in between different connections, so this being difficult does make a lot more sense in that context as well.