1. The point is that the prevailing theory for many, many years was based on DNA, not RNA and it did not deter scientists.
2. RNA world theory still has odds at 1 in 4.29 x 10^40. Though the theory is that billions of "trials" were taking place simultaneously, (a) billions is still but a blip when you consider how staggering the odds are, and (b) it doesn't take into account the birthday paradox, which would necessitate that the billions of trials would yield billions of repetitions, blunting the effect of so many simultaneous trials.