Methamphetamine explained simply:; Imagine you got guests at a party (same analogy I did for cocaine) these guests are your happy chemicals (dopamine, serotonin, norepinephrine) now imagine you bring Mr meth to your party. He brings TONS and TONS of guests to your party and locks the doors so no one can get out. when you have these many guests at the party, and none can escape, you will feel the greatest, most confident, amazing and powerful high you will ever feel. on the latter, cocaine just blocks the door. that's why meth users tweak more than coke users.