It's a "meme without words" meant to compare a common item to a muppet. Do you know who the Muppets are? Beaker is the Muppet on the right side of the meme. He always opens his mouth like that, especially when the muppet who is a scientist tries to make Beaker eat something dangerous. To the right of the faucet Is something that looks like Beaker saying "noooo!!!"