Supernova can create many things out of light, and it isn’t just limited to weapons…

Saike: *cough cough* what the fu- *cough*

X: what is that- *explosion*

Sot: I am stone, you can't infect me with a plague.

Chario: can angelic beings get sick?

Astra, data, Terra, and nobasu: *immune because they're robots*

Creatie and Tsar: *immune because they are crystals, and therefore not biological beings*

Collector: *immune because POWER*