Chris Sununu said that this is not what Republicans who are conservatives should do.
Your Apples versus Oranges comparison doesn't fit. In the first place Biden was trying to mitigate the effects of a deadly virus that his predecessor grossly mishandled. De Santis took on Disney because of their "Pride," events that flew in the face of his bigotry and homophobia.
Secondly, the US government has a vested interest in the health of the employees of a contractor. A COVID outbreak among a contractor's staff, could leave the government without necessary services to do its job. De Santis' only interest was to spread the hatred of one group of Americans have for another group.
Finally, the overwhelming majority of healthcare experts disagree with your politically based assessment that Vaccines are unnecessary.