I love it!
I like how you made the knifeboi and the amalgameme's role a perfect fit in the storyline, and 401 and Mr trollface seem great too!
But for one suggestion for an improvement, the amalgameme does occasionally summon minions but it doesn't run away and will always be aggresive at anyone that comes near. it will only stop fighting when you hurt it enough that starts to melt and eventually collapses and falls to the ground, scattering fragments of memes everywhere.