First of all, I don't see this as NSFW. Second, once submitted creators of a meme cannot mark it NSFW anymore, but moderators can, so you will have to mark it NSFW yourself if you really think it should be marked like that.
A mere mention in a way like this.... no...
Of course you can fill in that this means the girl has cheated, but before I think of NSFW the stuff must be more direct onto the subject than this.