ewww..yeah.
super mutants with a 38 is no Bueno.
I play a sneaky sneak.so have a lot of points in agi and luck.
you have a 10mm?
that's my go-to ,when it is modified it is a beast.takes out ghouls bing bang bong..
a modified 50 cal is best for mutants though,with pts in agi you get more ap points for vats.
and always use a scope for headshots,especially with mutants.
also use the scope when you hear mutants so you can snipe the suiciders.
when a mob gets too close?
switch to double barrel shotgun for bloody gore,and big numbers.