If you're talking about memes on the front page - if you don't find the meme itself funny, there are usually enough comments under it going on already that you can join in a conversation going on that you do find interesting or funny (like a sidetrack).
But honestly there are so many memes coming out on imgflip that if you just skip the ones you don't find interesting and comment on the ones you do like, you should still have plenty of memes.