I think the first 4-5 pages or so are the hottest. I like to dive into the comments there, 'cause that's where the real fun begins. After that I look at 'latest' memes to find rising, front-page worthy memes. I might go 10-15 pages deep there and as soon as I do, the mods load up another batch, so I kinda start again. Amazing how much time this can suck up!