If I'm to be honest, it takes alot of f**king luck and alot of people thinking that you're more cool than you really are...but seriously...I was a nobody 2 months ago. I had a few good memes but nothing too extraordinary I had about 6000 points or so...then someone told me the key was to comment like crazy and be as funny as possible...
Now I don't know about anyone else, but I put a lot of thought into my memes whether they're comment memes or memes for submission...before you know it, I was top commentor quite a bit...I think THAT'S how I got popular initially, because not long after that I got my first front page meme...
imgflip.com/i/rn46t . The comment section of this meme is probably the reason why people remember me to this day...in my opinion, I believe the only reason I make front page so often now is because I'm already "popular"...sure my memes are funny, but so are alot of other people's.
But...funny comments is where it all begins...if you "stand out" there, you WILL get noticed eventually...