It's a common misconception that bullets are capable of remaining airborne after being shot into the air. The closest you will get to that kind of speed, where the bullet would escape the atmosphere and no longer be affected by gravity, is the .900 JDJ round, which is not shoulder fired, therefore you would need a special mount to shoot the gun into the air. The only occasion in which it would be capable of killing someone is if the round was .40 caliber or higher (in pistol terms); a round smaller would probably not have the velocity capable of killing force. Plus, it would have to land in certain areas of the body to prove lethal, so to answer the question and this comment I am replying to, it will not escape Earth's gravitational reach, and it will probably not kill anyone if it comes down and hits them.