The concept of Israel as "ground zero" involves several key passages:
Zechariah 14:2-4: Describes a final gathering of all nations against Jerusalem for battle, ultimately culminating in the Messiah's feet touching the Mount of Olives.
Ezekiel 38-39: Prophesies a massive invasion of Israel in the "latter days" by a coalition of nations (often interpreted as Gog and Magog).
Luke 21:20: Records Jesus prophesying that Jerusalem will be surrounded by armies prior to the end.