I agree, my favorites from cartoon network are Ed Edd n Eddy, Powerpuff Girls, Dexter's Laboratory, Courage the Cowardly Dog, Johnny Bravo, Cow and Chicken and I.M. Weasel, and etc.
Things went downhill for them whenever they decided to make CN Real, which did not last long and was a terrible idea from the get-go, because it's called CARTOON Network, which means it's a channel specifically designed and created for animation only. It's as unfitting as putting a nature documentary on the food network, as CN Real was nothing but a desperate attempt to be like Disney XD and Nickelodeon as in being a kids' channel that had both Live-Action shows and animated shows. What they failed to realize is with their name being Cartoon Network, it means they can and should only be dedicated to anything animated.