Destiny 2: The Witch Queen received "generally favorable" reviews, according to review aggregator Metacritic.[24][25][26]
GameSpot praised the campaign for incorporating elements from raids and dungeons, writing that, "Levels drip-feed you new mechanics and ideas all along the way so that it all comes together in the boss fight, and coupled with Destiny 2's already excellent combat foundation, it makes for an intensely fast-paced, hectic experience".[27] Game Informer liked the new location, the Throne World, "On one side is the towering edifice of Savathûn’s sprawling palace grounds... That aesthetic gives way to a miasmic otherworldly swamp that feels dirty and overgrown. At both ends, there are secrets to uncover and impressive sights to see".[28] GamesRadar+ enjoyed the balancing of the campaign, "the Witch Queen campaign, particularly its Legendary mode, is a superb balance of challenge and power fantasy. Legendary feels just right. It's excellent in co-op... missions spit out twice the loot on Legendary, which makes the Power leveling process even easier".[29]
PCGamesN felt the new raid was the best in series history, "There are important roles for every player in each encounter, a good mix of different forms of challenge, and two excellent bosses which demand more from players than simply sitting in a Well of Radiance every damage phase".[30] While liking the new activities, GameSpot criticized the new weapon crafting system as being overly convuluted, "The system generally feels a bit too grindy in its earliest iteration--a lot of unlocking weapons and their various upgrades still requires a huge reliance on random drops".[31] IGN praised the Hive Guardians as adding a unique challenge to Destiny 2, "Victory against these formidable foes requires smart gunplay, patience, and most importantly, that you remember to quickly run and crush the enemy Ghost before it can revive them. A challenging new enemy type that forces you to think about how you approach an encounter like this is exactly what Destiny has needed to spruce up combat".[32]