In The CW's "The Flash", there is a character named Ralph Dibny, the "Elongated Man". In one Season 4 episode, he travels mid-combat by swinging from the rooftops, in a manner similar to Spider-Man's. When later questioned, Ralph claims he got the idea "from a comic book".
Name one hero who utilizes that technique apart from Spidey.
Furthermore, if the Spider-Man comics exist, it is implied that every hero he ever comes into contact with similarly exists, and so forth.
If that's not enough evidence, Spider-Man's presence implies Stan Lee and Steve Ditko exist, which means at the VERY least, every hero they have made and every hero those characters have met exist/exists.