My unbiased (clearly biased) opinion:
Plague Doc could not stand up to even a level 65 Hydreigon with the moves:
Crunch
Hyper voice
Dragon pulse
Earthquake
Applied. Reason being, earthquake would probably damage any structure enough to cause debris to fall or even cause the entire structure to collapse, trapping SCP-049 under the rubble until SCP foundation squads arrived. Even if the structure is strong enough to survive, Hydreigon has the ability Levitate. In Pokémon, this prevents ground type moves from affecting it. In this scenario, it’s likely Hydreigon can just float out of reach and use Dragon Pulse and Hyper Voice. If taught Dragon Tail, one hit would immediately end the battle, causing the opponent to flee. (In a trainer battle this switches Pokémon).