There are 2 ways to do so...
1. Open the same video in a new tab, this will reroll the add thing causing 1 of the 2 outcomes, the first completely gets rid of the add the other night make it skippable.
2. Pause the video, go do something else, come back after awhile and the add should have been skipped.
This stuff won't work on normal youtube, u would have to be on it in a browser such as chrome or microsoft edge.