The TPP was a global trade organization that involved countries from all continents. The primary profiteers would have been bankers, healthcare providers, and transportation providers. They would have made their profits by gouging regular people like you and me as well as businesses. The end result would have been that the top .00001% would have become even richer and the top 1% would have been pushed closer to everyone beneath them. Basically the super duper rich would become even more super duper rich and everyone else would be screwed, even the plain super rich.
NAFTA stands for North American Free Trade Agreement. It's a guideline for how Canada, the US, and Mexico trade with each other. Like every single other deal the US has been engaged in, it heavily favored the other countries involved. Trump is re negotiating our trade deals so our country can quit hemorrhaging money. He's already had tremendous success in Europe and they hate him for it, but that's not NAFTA related.