After graduating from a state university with a major and two minors in relevant fields. 60+ applications sent with hardly anything back

What was your major?

Expand your horizons. Don't plan on living back in your hometown for a while. I've not been able to find work that matched my degree in either my home town or where I lived when I got the degree. So be prepared to travel.

Also, sometimes it's not what you know, but who you know.

My degree was general enough that I was able to use staffing services for employment for several years.

An actual explanation I got from a prospective boss. Needless to say, I'm glad that I didn't end up working for that asshole.

College is about the process. Process of learning responsibility, getting along with others, living on your own, learning new things and meeting new people but most portably hard work and dedication.
Your field means nothing unless you're a doctor, lawyer, teacher or nurse. Expand your search!!