The September 11 attacks of 2001 caused the deaths of 2,996 people, including 2,977 victims and 19 hijackers who committed murder–suicide. Thousands more were injured, and long-term health effects have arisen as a consequence of the attacks. New York City took the brunt of the death toll when the Twin Towers of the World Trade Center complex in Lower Manhattan were attacked, with an estimated 1,600 victims from the North Tower and around a thousand from the South Tower. Two hundred miles southwest in Arlington County, Virginia, another 125 were killed in the Pentagon. The remaining 265 fatalities included the ninety-two passengers and crew of American Airlines Flight 11, the sixty-five aboard United Airlines Flight 175, the sixty-four on American Airlines Flight 77 and the forty-four who boarded United Airlines Flight 93. The attack on the World Trade Center's North Tower single-handedly made 9/11 the deadliest act of terrorism in human history.